An experimental study evaluating the effect of sodium carboxymethylcellulose on the prevention of postoperative intraabdominal adhesions

Intraabdominal adhesions may be acquired or congenital. Most are acquired as a result of peritoneal injury caused by abdominal surgery. They are induced by the inadvertible dissection and retraction of tissues and organs during the course of operation [4 ,6, 14]. Injury or inflammation of the peritoneum results in production of a protein-rich serosanguineous exudate. Coagulation of this exudate results in the adhesion of injured peritoneal surfaces within three hours [21]. Under normal circumstances, the majority of early fibrinous adhesions are lysed and absorbed within 48 to 72 hours. This adhesions are termed reversible adhesions. However, in some cases, fibrin may remain and become invaded by fibroblasts, ARTICLE ORIGINAL